منابع مشابه
Inhibitory Plasticity in Auditory Cortex
Arguably the most important property of neuronal circuits in general, and of cortical circuits in particular, is plasticity--the ability to change in response to past experience. While many studies of plasticity emphasize changes in excitatory transmission, in this issue of Neuron, Galindo-Leon et al. demonstrate the important role that increased inhibition may play in shaping cortical response...
متن کاملAuditory Plasticity: Vocal Output Shapes Auditory Cortex
Studies in humans and songbirds have revealed a close link between vocal output and hearing. Now experiments in marmosets have shown that self-generated vocalizations can modulate the activity of neurons in the auditory cortex and even remodel their response properties.
متن کاملDevelopment of inhibitory timescales in auditory cortex.
The time course of inhibition plays an important role in cortical sensitivity, tuning, and temporal response properties. We investigated the development of L2/3 inhibitory circuitry between fast-spiking (FS) interneurons and pyramidal cells (PCs) in auditory thalamocortical slices from mice between postnatal day 10 (P10) and P29. We found that the maturation of the intrinsic and synaptic proper...
متن کاملPlasticity during motherhood: changes in excitatory and inhibitory layer 2/3 neurons in auditory cortex.
Maternal behavior can be triggered by auditory and olfactory cues originating from the newborn. Here we report how the transition to motherhood affects excitatory and inhibitory neurons in layer 2/3 (L2/3) of the mouse primary auditory cortex. We used in vivo two-photon targeted cell-attached recording to compare the response properties of parvalbumin-expressing neurons (PVNs) and pyramidal glu...
متن کاملDevelopmental plasticity of auditory cortical inhibitory synapses.
Functional inhibitory synapses form in auditory cortex well before the onset of normal hearing. However, their properties change dramatically during normal development, and many of these maturational events are delayed by hearing loss. Here, we review recent findings on the developmental plasticity of inhibitory synapse strength, kinetics, and GABAA receptor localization in auditory cortex. Alt...
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ژورنال
عنوان ژورنال: Neuron
سال: 2009
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2009.05.017